I kēia mau lā iho nei, ua ʻāpono kūhelu ʻia e ka National Medical Products Administration o Kina ka hui pū ʻana o Anlotinib Hydrochloride a me Penpulimab e Chia Tai Tianqing no ka mālama mua ʻana i ka maʻi hepatocellular carcinoma holomua. ʻO kēia ka ʻumi o nā hōʻailona i ʻāpono ʻia no Anlotinib Hydrochloride, e hōʻike ana i kahi koho hou koʻikoʻi ma ke kahua o ka mālama ʻana i ka maʻi kanesa ate holomua. Hoʻokumu ʻia kēia lāʻau lapaʻau ma kahi noiʻi lapaʻau Phase III i paʻi ʻia ma ka puke pai oncology kaulana o ka honua *The Lancet Oncology*, me kāna ʻikepili hopena kupaianaha e lawe mai ana i ka manaʻolana hou i nā poʻe maʻi ma ka honua holoʻokoʻa.
**Ka Holomua Noiʻi: Hoʻolōʻihi nui i ke ola a hōʻemi i ka pilikia o ka maʻi**
ʻO ke aʻo ʻana, i kapa ʻia ʻo ALTN-AK105-III-02, he hoʻokolohua lapaʻau Phase III multicenter, randomized, open-label, parallel-controlled i hoʻolālā ʻia e loiloi i ka hana o Anlotinib Hydrochloride i hui pū ʻia me Penpulimab e kūʻē i ka lāʻau maʻamau kuʻuna ʻo Sorafenib i ka lāʻau lapaʻau laina mua o ka hepatocellular carcinoma holomua. Ua kākau inoa ke aʻo ʻana i ka huina o 649 mau maʻi kanesa akepaʻa holomua, kahi kokoke i 41% i loaʻa i ka macrovascular invasion, a ma kahi o 49.2% he kiʻekiʻe nā pae alpha-fetoprotein (≥400 ng/mL). Hōʻike pinepine kēia mau ʻano i nā pilikia lapaʻau nui aʻe.
He mea hoʻoikaika nā hopena o ke aʻo ʻana:
- **Ka Hoʻolōʻihi Koʻikoʻi ʻana o ke Ola me ka ʻOle o ka Holomua:** ʻO ka manawa ola waena me ka ʻole o ka holomua i ka hui hoʻōla hui pū ʻana ua hiki i 6.9 mau mahina, ʻoi aku ka nui ma mua o 2.8 mau mahina i ka hui kaohi, me ka emi ʻana o 47% i ka pilikia o ka holomua ʻana o ka maʻi a i ʻole ka make.
- **Hoʻomaikaʻi ʻIke ʻia i ke Ola Holoʻokoʻa:** ʻO ke ola holoʻokoʻa waena i ka hui hoʻōla hui pū ʻia he 16.5 mau mahina, hoʻohālikelike ʻia me 13.2 mau mahina i ka hui kaohi, e hōʻike ana i ka emi ʻana o 31% i ka pilikia o ka make.
ʻAʻole hōʻike wale kēia ʻikepili "dual positive endpoint" i nā pono o kēia lāʻau lapaʻau i ka hoʻopaneʻe ʻana i ka holomua o ka maʻi akā hōʻike pū kekahi i nā holomua nui i nā pono ola holoʻokoʻa, e hāʻawi ana i nā koho lapaʻau ʻoi aku ka maikaʻi no nā poʻe maʻi me ka maʻi kanesa ate holomua.
**Ke Keʻena Hoʻokele Honua o ka Halemai Oncology o ka ʻĀpana Hema o Beijing: Kou Hoa Kūʻē i ke Kanesa ma ka Honua**
I ke alo o ke kanesa, he mea nui ka loaʻa ʻana o ka ʻike lapaʻau kūpono a me ke kākoʻo lapaʻau loea i ka manawa kūpono. Ua hoʻolaʻa ʻia ka Beijing South Region Oncology Hospital International Department i ka hāʻawi ʻana i nā lawelawe hōʻoia a me ka mālama ʻana i ka oncology no nā maʻi o ka honua, me nā kūkākūkā ʻana ma nā lāʻau lapaʻau hou loa, ka hoʻolālā lapaʻau pilikino, a me ke kōkua kamaʻilio ʻana ma waena o nā ʻōlelo. Hana pū mākou me nā ʻoihana noiʻi kūloko a me ka honua e hōʻoia i ka loaʻa ʻana o ka pōmaikaʻi o nā maʻi mai nā holomua hou e like me ka lāʻau lapaʻau hui pū ʻana o Anlotinib Hydrochloride.
**ʻIke Hoʻokaʻaʻike: Eia mākou e lawelawe iā ʻoe**
Inā ʻoe a i ʻole kāu poʻe aloha e ʻimi nei i nā koho lapaʻau no ke kanesa akepaʻa holomua a i ʻole nā maʻi puʻupuʻu ʻē aʻe, e ʻoluʻolu e hoʻokaʻaʻike koke mai iā mākou ma o kēia mau ʻano hana. E hāʻawi kā mākou hui loea i nā hoʻolauna lapaʻau kikoʻī, ke alakaʻi ʻana i nā kaʻina hana lapaʻau, a me ke kākoʻo no nā poʻe maʻi o ka honua:
- **Kelepona:** 400-880-3716
E kāhea i kēia helu e kamaʻilio pololei me kā mākou mau mea hoʻonohonoho maʻi honua no nā kūkākūkā wikiwiki a me ke kōkua hoʻonohonoho.
- **WeChat:** 17801183037
E hoʻohui i kā mākou moʻokāki WeChat kūhelu e loaʻa i ka ʻike lapaʻau manawa maoli, nā nīnau pūnaewele, a i ʻole nā kūkākūkā wikiō.
- **Leka uila:**
① 100085_010@163.com
② myimmnet@163.com
E hoʻouna i nā moʻolelo lapaʻau a i ʻole nā nīnau i kā mākou leka uila, a e hāʻawi kā mākou hui loea i nā ʻōlelo aʻoaʻo lapaʻau pilikino.
**No ke aha e koho ai iā mākou?**
- **Ke komo ʻana i nā lāʻau lapaʻau ʻoi loa:** Ke hahai mau nei mākou i nā ʻano lapaʻau oncology honua e hōʻoia i ka loaʻa ʻana o nā manawa kūpono i nā mea maʻi e loaʻa ai nā hopena hou e like me ka lāʻau lapaʻau hui pū ʻana ʻo Anlotinib Hydrochloride.
- **Nā Lawelawe ʻŌlelo Helu:** Hāʻawi mākou i ke kākoʻo ma nā ʻōlelo he nui, me ka ʻōlelo Pelekania, e hoʻopau i nā pale kamaʻilio a hōʻoia i kahi ʻike maʻalahi no nā maʻi o ka honua.
- **Kōkua Piha:** Mai nā noi visa a me nā hoʻonohonoho noho ʻana a hiki i nā hahai ʻana i ka mālama ʻana, hāʻawi mākou i nā lawelawe akahele hoʻokahi.
He heihei kūʻē i ka manawa ka mālama ʻana i ke kanesa. Ua lawe mai ka ʻae ʻia ʻana o ka hui pū ʻana o Anlotinib Hydrochloride i ka manaʻolana hou i nā poʻe maʻi me ke kanesa akepaʻa holomua. Ma hea ʻoe e noho ai, ua mākaukau ka Beijing South Region Oncology Hospital International Department e lilo i hoa kūpaʻa nou i kāu huakaʻi kūʻē i ke kanesa. E kāhea mai iā mākou i kēia lā e hoʻomaka i kāu huakaʻi mālama pilikino!
**E hoʻomanaʻo i kā mākou ʻike pili:**
Kelepona: 400-880-3716
WeChat: 17801183037
Email: 100085_010@163.com or myimmnet@163.com
Ke kakali nei mākou i ka hāʻawi ʻana iā ʻoe i ke kākoʻo lapaʻau akamai a me ke aloha!
Ka manawa hoʻouna: Ian-27-2026